Acetylcholinesterase Inhibitors
The following medicines work by preventing an enzyme from breaking down a substance called acetylcholine in the brain, which helps nerve cells communicate with each other.
(Donepezil is also used to treat more severe Alzheimer’s disease).
These medications were clinically trailed with evidence showing they can also help treat dementia with Lewy bodies and Parkinson’s disease dementia, as well as those with a mixed dementia diagnosis of Alzheimer’s disease with vascular dementia.
There is little difference between these medicines in their effectiveness.
If hallucinations are one of the main symptoms, then Rivastigmine may be preferred.
Side effects: Side effects may consist of nausea and loss of appetite; these should be relieved after two weeks of taking the medication.
∙Memantine (Namenda)
This medication is for moderate or severe Alzheimer’s disease, dementia with Lewy bodies and those with a combination of Alzheimer’s disease and vascular dementia.
This is a suitable option for those who are unable to take or cannot tolerate Acetylcholinesterase Inhibitors.
Memantine works by blocking the effects of excessive amount of a chemical in the brain called glutamate.
Side effects: Side effects may consist of headaches, dizziness and constipation, these are usually only temporary.